Modafinil is a wake-promoting drug that’s used to treat sleep disorders like narcolepsy and obstructive sleep apnea. It’s also known as a nootropic, and it has been shown to improve cognitive function in some studies.
However, other studies have been mixed. And many experts are concerned about the abuse of prescription drugs like modafinil by healthy people who want to boost their brain power.
1. Boost Your Vitamin D Levels
Modafinil 200 Australia is a popular drug that many use to boost their cognitive abilities. It has been shown to increase alertness, enhance memory, and improve problem-solving skills. However, this smart drug may not be as good as people think. A new study found that Modafinil impairs people’s ability to respond to questions in a creative way.
Modafinil, also known by the brand name Provigil, is a medication approved by the Food and Drug Administration to treat narcolepsy and other sleep disorders. It works by boosting dopamine, norepinephrine, and histamine in certain areas of the brain to promote wakefulness and reduce fatigue.
Modafinil is available by prescription only, making it less accessible than nootropic supplements like Mind Lab Pro(r). Mind Lab Pro(r) is a safe and effective nootropic that contains a blend of 11 natural ingredients including Citicoline, Bacopa Monnieri extract, Organic Lion’s Mane Mushroom, Phosphatidylcholine, L-Glutamine, and GABA agonist Alpha GPC. It is also stimulant-free and can help you stay focused without jitters or energy crashes. It’s been formulated for long-term brain health and has a reputation as one of the best cognitive enhancers on the market.
2. Eat a Healthy Diet
Developed to treat narcolepsy, modafinil is widely used off-label as a cognitive enhancer. It can improve planning, flexibility, memory and learning, and performance on time-limited cognitive tasks. However, the benefits vary depending on the task and can be offset by other medications and factors.
A recent study found that modafinil has a unique physiological profile compared to other stimulants, enhancing prefrontal cortex cognitive information processing and dampening the amygdala’s reactivity to threat. Nevertheless, the study was short-term and it’s unclear what effect the drug will have on the brain in the long term.
Cognition-enhancing drugs can cause side effects such as insomnia, headache and stomach ache in some people, but they’re often worth the risks for those who want to improve their mental functioning. But there are ethical concerns about healthy people using cognition-enhancing drugs without a medical condition, particularly in light of recent research suggesting that the drugs can trigger psychosis or mood changes.
3. Exercise Regularly
Despite the fact that many people have used modafinil off-label to enhance their performance, there are few studies of its long-term safety or effectiveness in healthy humans. Most of the studies have been conducted in a controlled scientific setting and only looked at the effects of a single dose, says neuropsychologist and review co-author Anna-Katharine Brem.
One double-blind study in which emergency department physicians underwent simulated night shifts found that modafinil 200 mg significantly improved accuracy on the WCST and Hayling Sentence Completion Task relative to placebo (Gill et al, 2006). Modafinil also heightens alertness in a sleep-deprived state in healthy volunteers. A randomized, placebo-controlled fMRI study of eight healthy adults showed that a single dose of modafinil 200 mg improved working memory performance and associated cortical activation on the serial reversal alternation task compared to placebo (Thomas and Kwong, 2006).
Modafinil’s structural similarities to MPH suggest that it enhances cognitive function by acting on dopamine and glutamate transmission. However, unlike MPH and other stimulants, modafinil does not appear to increase blood pressure or heart rate in healthy volunteers, implying that it is less likely to have adverse cardiovascular consequences.
4. Get Enough Sleep
A common side effect of Modafinil is insomnia, so it’s important to make sure you get enough sleep when using this smart drug. Getting at least 8 hours of sleep per night is a great start and will help you stay alert throughout the day. You should also avoid consuming any caffeine or nicotine before bed.
Getting plenty of sleep will also keep you mentally sharp, so try to stick to your regular sleeping schedule. If you have trouble falling asleep at night, try avoiding any electronic devices and engaging in some light reading or other relaxing activity before bed.
Modafinil has been shown to enhance cognitive function in healthy subjects. It can also reduce feelings of fatigue and apathy. A study involving six helicopter pilots who were kept awake for two 40-hour periods found that when given three 200 mg doses of modafinil, their flight simulation performance was maintained at levels comparable to those of a fully rested group. Moreover, the placebo group showed a significant drop in alpha and delta power in the EEG, which was correlated with decreased adenosine levels in the basal forebrain.
5. Stay Stress-Free
While it was developed to treat narcolepsy, modafinil has been used off-label as a cognitive enhancer. The drug is considered to be the first well-validated pharmaceutical nootropic (a cognition enhancing agent). It has been shown to improve alertness and concentration without the usual side effects of traditional psychostimulants. This makes it a potentially powerful tool in the fight against combat fatigue, which can be caused by a combination of factors including sleep deprivation, circadian disruption, extended duty periods, and fear or anxiety.
It has also been found to improve performance on cognitive tasks such as the WCST, the Hayling Sentence Completion Test, and a version of the digit-symbol task in healthy individuals. One study found that a 3-week course of modafinil reduced errors on the WCST and improved performance on the digit symbol substitution task, both in comparison to placebo. This was associated with activation of the dorsolateral prefrontal cortex and anterior cingulate cortical regions measured by fMRI.
However, it is important to remember that the cognitive enhancing effects of Modafinil are only temporary and do not last throughout the day. It is also not known whether the drug is safe for long-term use.
